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Figure 6 | Advances in Difference Equations

Figure 6

From: Modeling bacterial resistance to antibiotics: bacterial conjugation and drug effects

Figure 6

Effects of delays in drug administration. (a) Antibiotic concentration changes according to time for three scenarios of a delay in administering an initial dose of a therapeutic agent: (1) no delay (2) delay of two days, and (3) delay of four days. (b)–(c) Prevalence of sensitive and resistant bacteria after administering drug M and N, respectively. (d) When there is a delay in administering the second dose of an antimicrobial agent, the antimicrobial concentration changes with time according to three scenarios: (1) no delay in the second dose, (2) delay of 12 hours, and (3) delay of 24 hours. (e)–(f) Prevalence of sensitive and resistant bacteria when there is a delay in administrating the second dose for drug M and N, respectively (\(S(0) = 1.2 \times 10^{8}\) and \(R(0) = 2.3 \times 10^{8}\))

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