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Theory and Modern Applications

Figure 3 | Advances in Difference Equations

Figure 3

From: Stability, Hopf bifurcation and effects of impulsive antibiotic treatments in a model of drug resistance with conversion delay

Figure 3

Time series solution under impulsive drug treatments and delay. Numerical solution of (32)–(33) where the sensitive and resistant strains undergo impulsive jumps every time drug treatment is applied. Here, \(x ( 0 ) = 0.3\), \(y ( 0 ) = 0.4\), \(z ( 0 ) = 0.5\), \(a_{1} = 2.407407\), \(a_{2} = 0.023077\), \(a_{3} = 0.00196\), \(a_{4} = 0.0007\), \(\omega _{1} = 0.7\), \(\omega _{2} = 0.7\), \(\omega _{3} = 0.7\), \(K_{S} = 0.7\), \(K_{\gamma } = 4.3\), \(K_{R} = 5.0\), \(\varepsilon _{r} = 0.9\), \(\gamma = 4.0\), \(\mu = 0.01\), \(z^{*} = 5.0\), \(\tau = 0.1\) and \(\psi _{R} = 0.5\), \(r = 0.1\), \(p = 1.0\), \(T = 3\)

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