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Table 2 Parametric values used in the model simulations shown in Figures  3 - 5

From: Modeling fibrous cap formation in atherosclerotic plaque development: stability and oscillatory behavior

Parameter Meaning Value (Figures  3 , 4 ) Value (Figure  5 ) Unit
\(d_{1}\) Reaction rate constant in (1) 1.520 × 104 1.520 × 103 \(\mbox{g}^{-1}~\mbox{cm}^{3}~\mbox{wk}^{-1}\)
\(d_{2}\) Variation constant in (2) 1.429 0.8024 \(\mbox{g}^{-1}~\mbox{cm}^{3}~\mbox{wk}^{-1}\)
\(d_{O}\) Degradation rate of \(L_{O}\) 6.048 × 10−1 0.01 wk−1
\(d_{M}\) Death rate of M 6.048 × 10−1 0.01 wk−1
\(d_{F}\) Death rate of F 4.285 × 10−3 0.25 wk−1
\(d_{C}\) Degradation rate of \(C_{O}\) 0.01 0.01 wk−1
\(d_{c}\) Degradation rate of \(C_{M}\) 0.01 0.1 wk−1
\(d_{S}\) Intrinsic death rate of S 1.08 0.1 wk−1
\(d_{E}\) Removal rate of E 0.5 0.05 wk−1
\(k_{c}\) Saturation constant of migration 10−4 10−2 wk−1
\(m_{s}\) Removal rate of S to form E 1.68 0.5 wk−1
\(s_{1}\) Production rate of \(C_{O}\) 6.05 × 10−3 1.520 × 103 wk−1
\(s_{2}\) Immigration rate of M fostered by \(C_{O}\) 10.2 0.8024 wk−1
\(s_{3}\) Production rate of \(C_{M}\) 0.1814 0.01 wk−1
\(s_{4}\) Proportionality constant in production rate of S due to migration 1.814 0.01 wk−1
\(s_{5}\) Variation constant in production rate of E 6.0 0.25 wk−1
\(R_{f}\) Number of free radicals in oxidation process 0.02772 0.01 mg/ml
α Fraction of \(M L_{O}\) that goes into E production 0.5 0.6 -
β Fraction of \(M L_{O}\) that goes into F production 0.5 0.4 -
μ Proportionality constant in (8) 6.05 0.00238 wk−1
ρ Migration rate of S at vanishing \(C_{M}\) 7.5 0.001 \(\mbox{g}^{-1}~\mbox{cm}^{-3}~\mbox{wk}^{-1}\)
σ Growth rate of \(L_{l}\) 2.016 × 103 2.016 × 103 \(\mbox{g}^{-1}~\mbox{cm}^{-3}~\mbox{wk}^{-1}\)
p Proliferation rate of S [1.700,1.765] 0.4 wk−1