Λ

Constant production rate of healthy CD4+ Tcells from precursors

\(d_{T}\)

Natural death rate of healthy CD4+ Tcells

r

Logistic growth rate of healthy CD4+ Tcells

\(T_{\mathrm{max}}\)

Carrying capacity of healthy CD4+ Tcells

k

Infection rate of healthy CD4+ Tcells by free infectious virus

η

Fraction of infections leading to latently infected CD4+ Tcells

\(d_{L}\)

Death rate of latently infected CD4+ Tcells

\(d_{I}\)

Death rate of productively infected CD4+ Tcells

a

Activation rate from latently to productively infected CD4+ Tcells

N

Average number of free virus released by a productively infected CD4+ Tcell during its mean lifetime \(1/d_{I}\)

c

Clearance rate of free virus

\(n_{rt}\)

Drug efficacy of RTI \((0 \leq n_{rt} < 1)\)

\(n_{p}\)

Drug efficacy of PI \((0 \leq n_{p} < 1)\)

τ

Time delay for transformation from latently to productively infected CD4+ Tcells
